This issue of the journal focuses on current diagnostic modalities used to diagnose and manage patients with pulmonary hypertension (PH) and especially the more complex and severe form, pulmonary arterial hypertension (PAH). Thanks to the impressive evolution of this field in recent years, physicians who take care of patients with PH are being faced with a very diverse population in whom PH etiology is frequently multifactorial. While potentially life saving, the cost and complexity of some of the treatments available for PAH mandate that clinicians perform a comprehensive evaluation of patients to confirm or exclude its presence. Likewise, given the